Explore the Extracellular Matrix using a Biocolor Kit

The ECM has been likened to a ‘glue’ that binds cells together in connective tissues.

It provides necessary biomechanical support to tissues, is responsible for the physical and biochemical maintenance of all cells within an organism, and plays a key role in cellular processes such as cell proliferation, differentiation and migration.

The Extracellular Matrix (ECM) is a fundamental part of living organisms, composed primarily of water, proteins, and polysaccharides. Its main structural proteins are fibrous in nature, with collagen and laminin being key examples. This fibrous network holds hydrogel-forming molecules such as the glycosaminoglycans, heparin and hyaluronic acid. A diverse range of other molecules are also present, including growth factors and Matrix Metalloproteases (MMPs).

Analysing the Extracellular Matrix (ECM) helps us understand how organisms develop and age, as well as finding ways to treat diseases like cancer. Through advancements in Bioengineering, we hope to control ECM formation for fixing damaged tissues. Purified ECM components are becoming increasingly valuable in industries such as food production and cosmetics.